Excretion of 5-Hydroxy Indolyl-Acetic Acid after Surgery

Radioimmunoassay of 5-hydroxy-3-indole acetic acid.

A direct radioimmunoassay of the methyl ester of urinary and serum 5-hydroxy-3-indole acetic acid is described. The antiserum, raised in a rabbit against a conjugate of bovine serum albumin with 5-hydroxytryptamine hemisuccinamide, contained two antigenic fractions, one binding N-acyl 5-hydroxytryptamine, and the other binding methyl ester of 5-hydroxy-3-indole acetic acid, and N-acyl 5-hydroxy...

Excretion of 5-hydroxyindolyl acetic acid (5HIAA) in migraine.

Urinary excretion of 5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid in children.

5-S-Cysteinyldopa (5SCD) and 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI2C) are formed during biosynthesis of melanins. They are used as indicators of pigment formation and markers of melanoma progression in adults and could possibly be used as markers of activity, growth and even malignant transformation in large pigmented naevi in children. We investigated the urinary excretion of thes...

Excessive urinary 5-hydroxy-3-indole acetic acid in the absence of a metastatic carcinoid.

THE colorinietric test allegedly specific for the malignant careinoid syndrome was recently observed to be strongly positive in 2 patients who did not have this disease. Observation of excessive elevation of urinary 5-hv-droxy-3-inidole acetic (5-HIAA) by the qualitative chemical test of IJdenfriend and co-workers has beeni considered a specific. siunple, rapid, and reliable means of recognizin...

Simple determination of high urinary excretion of 5-hydroxyindole-3-acetic acid with ferric chloride.

We describe a method for determination of urinary 5-hydroxyindole-3-acetic acid, a metabolite of serotonin and tryptophan and a useful indicator of metastasizing carcinoid tumor. The analysis is based on the color development with ferric chloride added to the residue obtained on evaporating a diethyl ether extract of the sample that has been acidified with sulfuric acid and saturated with sodiu...